Esco

Esco Stainless Steel Weighing Chamber at Beximco Pharmaceuticals Ltd.


Jun 06, 2017

 

Esco Pharma completes Esco Groups’ Life Sciences expertise in Biocontainment by providing cGMP Flowhoods running on HMI/PLCs with 21 Cfr part 11 compliance designed as Class @ A2 Biological Safety Cabinets. As an option these can be tested during IOQ with KI Discus Containment testing to EN 12469 standards. In this application our flowhood was designed with a downflow velocity of 0.45 m/s and cooling coils to maintain temperature at 21˚C ±2˚. In addition, a dehumidification unit maintains <20% RH for weighing and dispensing of hygroscopic powders.

 

Figure 1. Class II Type B2 Biological Safety Cabinet (B2 Weighing Chamber)

Esco Product Information:

ITEM CODE: 2010861

General Specification, Labculture Class II, Type B2 (Total Exhaust) Biological Safety Cabinets
Model LB2-5B_ with SPL-5A0
External Dimensions (WxDxH) 1725 x 852 x 1795 mm 68.0” x 33.5” x 70.6”)
Internal/Work Area Dimensions (WxDxH) 1570 x 623 x 900 mm (61.8” x 24.5” x 35”)
Usable Work Area 0.75 m²
Tested Opening 254 mm (10”)
Certification Exhaust Volume 1016 m³/h (588 cfm)
Pressure 375 Pa/1.5 in H20
Concurrent Balance Exhaust Value* Volume 1853 m /h (1091 cfm)
Pressure 550 Pa /2.2 in H O2
Downflow ULPA Filter Typical Efficiency >99.999% for particle size between 0.1 to 0.3 microns,
per IEST-RP-CC001.3
Exhaust HEPA Filter Typical Efficiency >99.99% at 0.3 microns
Fluorescent Lamp >1400 Lux (>130 foot-candles)
Cabinet Construction Main Body Stainless Steel 304, 4B Finish. Walls: 1.2 mm(0.05")/18 gauge
Work Zone Stainless Steel 304, 4B Finish. Tray: 1.5mm(0.06")/16 gauge. Walls: 1.2 mm(0.05")/18 gauge
Electrical Rating Power rating: 1 220-240 VAC, 50 Hz, 1ø
Power rating: 2 110-130 VAC, 60 Hz, 1 ø
Power rating: 3 220-240 VAC, 60 Hz, 1 ø
Power rating: 7 100 VAC, 50/60 Hz, 1ø

 

Figure 2. Flow Hood (A2 Weighing Chamber)

Esco Product Information:

ITEM CODE: 2021146

Product Unit Flowhood
Airflow Class ISO Class 2
External Dimensions (WxDxH) 1600 x 1240 x 2412 mm (63.0” x 48.8” x 95.0”)
Internal Work Area Dimensions (WxDxH) 1500 x 750 x 900 mm (61.8” x 24.5” x 35”)
Material of Construction SS 304
Control Type SIEMENS PLC, SIEMENS HMI, ASHCROFT
Pressure Differential Transmitter (Closed Loop)
Chamber Condition RH 20 ± 10% 20˚ ± 2˚C (DWYRER RH CONTROL)
Filter Stages G4-H14
Airflow Velocity 0.45 m/s ± 20% (150 from diffuser)
Sound Level < 65 dBA (300 mm in front of the unit)
Light Level >600 Lux (From Working table)
Power Supply 230V, 50 Hz, 1 Ph
Dehumidifier Process rated Airflow 300 CMH, 200 Pa