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Airstream® Class III Biological Safety Cabinets

Class III Biological Safety Cabinets Picture

Esco Airstream Class III biohazard safety cabinets offer the highest level of product, operator and environmental protection from infectious/biohazardous aerosols and are suitable for microbiological work with agents assigned to biological safety levels 1, 2, 3, or 4. Designed for an absolute level of containment, they are frequently used for work involving the deadliest biohazards, bacteria, viruses and microorganisms. Manufactured to meet and exceed the latest Class III biohazard safety cabinet requirements of the EN 12469:2000.

Key Benefits:
  • Designed for BSL-4
  • Safer dual exhaust filters
  • Magnehelic pressure gauge


  • Exhaust air is double-filtered through high-quality ULPA filters (per IEST-RP-CC-001.3) with typical efficiency of >99.999% for 0.1 to 0.3 micron particles, better than HEPA filters.
  • Exclusive dual exhaust filters provide >100,000 times better protection than single-stage designs.
  • Microprocessor-based Esco Sentinel™ Silver control system provides visual / audible alarms for airflow.
  • Magnehelic* pressure gauge is mounted in the rear of the work zone for at-a-glance monitoring of work zone negative pressure.
  • Neoprene™ gauntlets are single piece leak-tested glove assemblies which guarantee maximum protection.
  • An integrated pass-through with interlocking doors, permits materials transfer without risk of environmental contamination.
  • Esco ISOCIDE antimicrobial surface on all painted surfaces minimizes contamination.
  • An angled cabinet front ensures an ergonomic working posture.
  • Cabinet operates at negative pressure relative to the laboratory in order to prevent migration of pathogenic materials out of the work area.

*Registered trademark of Dwyer Instruments, Inc.

Model No. External
Dimensions (mm)
Dimensions (mm)
Velocity (Inflow)
Velocity (Downflow)
1665 x 850 x 2250
1340 x 560 x 650
-275 Pa(m/s) /
-1.1 Wg(fpm)
220-240V,AC, 50Hz,1ø
AC3-4B2 110-120V,AC, 60Hz,1ø
1970 x 850 x 2250
1645 x 560 x 650
-275 Pa inside unit(m/s) /
-1.1 Wg(fpm)
220-240V,AC, 50Hz,1ø
AC3-5B2 110-120V,AC, 60Hz,1ø
2275 x 850 x 2250
1950 x 560 x 650
-275 Pa inside unit(m/s) /
-1.1 Wg(fpm)
220-240V,AC, 50Hz,1ø
AC3-6B2 110-120V,AC, 60Hz,1ø
Esco offers a variety of options and accessories to meet local applications. Contact Esco or your local Sales Representative for ordering information.

Electrical Outlets and Utility Fixtures
  • Electrical outlet, ground fault, North America
  • Electrical outlet, Europe / Worldwide

Cabinet Accessories
  • Anti Blowback Valve
  • Germicidal UV lamp
    • Controlled by automatic UV lamp timer through SentinelTM microprocessor control panel
    • Emission of 253.7 nanometers for most efficient decontamination
  • Ergonomic lab chair
    • Laboratory grade construction, meets Class 100 cleanliness; alcohol resistant PVC materials
    • Adjustable height 395-490 mm(15.6"-19.3")
  • Ergonomic foot rest
    • Angled, helps maintain proper posture
    • Adjustable height
    • Anti-skid coating, chemical resistant finish
  • Formalin Vaporizer
Request an End User Seminar Airflow

  • Ambient air is pulled into the cabinet through a disposable pre-filter, trapping larger particles and prolonging the life of the main filter. Air is then passed through the downflow ULPA filter into the work zone as a vertical laminar flow air stream, bathing the work surface in clean air.
  • The uniform non-turbulent air stream protects against cross contamination within and throughout the work area.
  • Near the work surface, the downflow air stream splits and exits the chamber through perforations around the perimeter of the work zone.
  • Air from work zone passes through the first ULPA exhaust filter below the work surface, before traveling through internal ducting and exhausting to the laboratory environment after passing through the second ULPA exhaust filter located above the cabinet's main chamber.

EN 12469, Europe ISO 14644.1 Class 3, Worldwide
IEST-RP-CC034.1, Worldwide
IEST-RP-CC007.1, Worldwide
IEST-RP-CC001.3, Worldwide
EN 1822 (H14), Europe
IEC 61010-1, Worldwide
EN61010-1, Europe
UL61010-1, USA
CAN/CSA-22.2, No.61010-1