
A Cradle for High Density Cells
CelCradle™ is a disposable bioreactor capable of high density cell culture for protein expression, virus and monoclonal antibody production. It is designed based on the concept of bellow-induced intermittent flow of media and air through porous matrices, where cells reside. This provides a low shear, high aeration, and foam-free culture environment.
During operation, the CelCradle™ bottle is partially filled with media and inoculated with cells. The media is raised and lowered alternately to submerge and expose the matrices, creating a dynamic interface between air and media on cell surface to maximize nutrient uptake and oxygen transfer.
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Esco Micro Pte. Ltd.
21 Changi South Street 1 Singapore 486777
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